Here you go, there are many studies published in NCBI pubmed. It’s just the quacks never bother look it up.
CONCLUSIONS:
The study confirms the efficacy of ozone concerning pain relief, functional improvement, and quality of life in patients with knee osteoarthritis.
CONCLUSION:
Ozone therapy is a significant modality for treatment of sudden sensorineural hearing loss; no complications were observed.
In conclusion, application of ozone on RAS lesions for 60 seconds reduced pain levels and enhanced ulcers’ healing by reducing ulcers’ size and duration.
CONCLUSIONS:
Oxygen/ozone treatment of herniated discs is an effective and extremely safe procedure. The estimated improvement in pain and function is impressive in view of the broad inclusion criteria, which included patients ranging in age from 13 to 94 years with all types of disc herniations. Pain and function outcomes are similar to the outcomes for lumbar discs treated with surgical discectomy, but the complication rate is much lower (<0.1%) and the recovery time is significantly shorter.
CONCLUSION:
Based on the current meta-analysis, intra-articular ozone injection efficacy was significantly superior to placebo and slightly lower to other control injections with non-significant difference. Therefore, ozone could be recommended as an efficient non-surgical treatment, durable for at least 3-6 months, in mild or moderate knee OA management.
CONCLUSION:
Ozone therapy proved effective in the short-term in relation to placebo and when combined with hyaluronic acid, but it was not superior to other current treatments.
https://www.youtube.com/watch?v=-UoLB6SprdM
Actually there are numerous double blind studies proven the efficacy of ozone therapy, problem is that the western quacks denies them or suppresses them or ignores them because it goes against their belief system. Allow me to share some of them:
PLoS One. 2017 Jul 24;12(7):e0179185. doi: 10.1371/journal.pone.0179185. eCollection 2017.
Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study.
CONCLUSIONS:
The study confirms the efficacy of ozone concerning pain relief, functional improvement, and quality of life in patients with knee osteoarthritis.
J Laryngol Otol. 2009 Jan;123(1):54-60. doi: 10.1017/S0022215108003770. Epub 2008 Oct 17.
Randomised, double-blinded, placebo-controlled, clinical trial of ozone therapy as treatment of sudden sensorineural hearing loss.
CONCLUSION:
Ozone therapy is a significant modality for treatment of sudden sensorineural hearing loss; no complications were observed.
Sci Rep. 2016 Jun 15;6:27772. doi: 10.1038/srep27772.
Ozone treatment of recurrent aphthous stomatitis: a double blinded study.
In conclusion, application of ozone on RAS lesions for 60 seconds reduced pain levels and enhanced ulcers’ healing by reducing ulcers’ size and duration.
There are many randomized controlled trials, double-blinded, placebo-controlled, meta-analysis and even systematic reviews about ozone such as these:
J Vasc Interv Radiol. 2010 Apr;21(4):534-48. doi: 10.1016/j.jvir.2009.12.393. Epub 2010 Feb 25.
A metaanalysis of the effectiveness and safety of ozone treatments for herniated lumbar discs.
CONCLUSIONS:
Oxygen/ozone treatment of herniated discs is an effective and extremely safe procedure. The estimated improvement in pain and function is impressive in view of the broad inclusion criteria, which included patients ranging in age from 13 to 94 years with all types of disc herniations. Pain and function outcomes are similar to the outcomes for lumbar discs treated with surgical discectomy, but the complication rate is much lower (<0.1%) and the recovery time is significantly shorter.
J Pain Res. 2018 Oct 25;11:2537-2550. doi: 10.2147/JPR.S175441. eCollection 2018.
An investigation into the efficacy of intra-articular ozone (O2-O3) injection in patients with knee osteoarthritis: a systematic review and meta-analysis.
CONCLUSION:
Based on the current meta-analysis, intra-articular ozone injection efficacy was significantly superior to placebo and slightly lower to other control injections with non-significant difference. Therefore, ozone could be recommended as an efficient non-surgical treatment, durable for at least 3-6 months, in mild or moderate knee OA management.
Acta Med Port. 2018 Oct 31;31(10):576-580. doi: 10.20344/amp.10330. Epub 2018 Oct 31.
[Ozone Therapy in Knee Osteoarthritis: A Systematic Review].
CONCLUSION:
Ozone therapy proved effective in the short-term in relation to placebo and when combined with hyaluronic acid, but it was not superior to other current treatments.
There you go, there are many studies published in NCBI pubmed. It's just the quacks never bother look up to it. :)
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